The Next Preventive Frontier May Be Right Under Our Noses

For something we rely on every minute of every day, the nose is remarkably overlooked.

That was the central theme of a recent Vital Stuff conversation between podcaster Gail Lebovic, MD, and Karen Parker-Davidson, DHA-APRN.  This exchange underscored a growing realization in medicine: nasal health is foundational to overall health, not an afterthought.

“We think about breathing only when something goes wrong,” Lebovic noted. “But oxygen is the one thing we can’t live without—even briefly.” The route that oxygen takes, Parker-Davidson emphasized, matters far more than most people realize.

Gail Lebovic, MD
Karen Parker-Davidson, DHA-APRN

The Nose as a Functional and Diagnostic Organ—Not Just a Passageway

Parker-Davidson, a clinician with more than three decades of experience across critical care, ENT, aerospace medicine, and medical devices, reframed the nose as a reactive organ—one with more than 60 distinct functions. Its job is not merely to move air, but to filter, humidify, warm, and regulate airflow before it reaches the lungs.

Nasal resistance is slow and sneaky, she explained, and is often mistaken for congestion. Congestion is acute and obvious. Resistance is cumulative, and insidious—quietly impairing airflow, oxygen exchange, sleep quality, posture, and even facial development over time.

“We can be breathing and still not be breathing well,” Parker-Davidson said.

Measuring What Patients Feel

That gap between subjective sensation and objective function, aka the Weber-Fechner Law, is where innovation enters the picture. Lebovic described how her work with NasoClenz revealed a consistent pattern: people reported they could “breathe better” almost immediately after using the nasal-cleansing gel—but there was no reliable way to measure that improvement.

Enter 4-phase rhinomanometry, a non-invasive standard diagnostic tool aimed at objectively evaluating nasal function. The non-invasive technique measures airflow and pressure in seconds during nasal breathing.  When Parker-Davidson applied it, the results were striking. Objective measurements showed a reduction of approximately 15% in nasal resistance within minutes of using NasoClenz.

“It wasn’t just a feeling,” Parker-Davidson said. “The data showed real physiologic change.”

The gel works by gently interacting with the nasal tissues inside the nose, more commonly known as the nasal turbinates. The nasal turbinates are particularly rich in histamine-responsive tissue and tend to swell during allergies or congestion. The application of NasoClenz helps airflow move more smoothly, while preserving the resistance needed for proper nasal function and lung protection.

A Post-Pandemic Nasal Awakening

Both clinicians agreed that the COVID-19 pandemic accelerated awareness of nasal health. With most respiratory viruses entering through the nose, the organ’s role as a biological gatekeeper became impossible to ignore.

“We’re in the middle of a nasal renaissance,” Lebovic said. “The nose is finally getting the respect it deserves.”

For Parker-Davidson, the goal now is education, translating complex airway science into practical, preventive strategies that help people breathe easier, sleep better, and perform better.

Breathing, after all, is the most basic act of survival. As this conversation made clear, how we breathe—and how well—may shape far more of our health than we ever imagined.


ICU Study Finds Simple Adhesive Step Improves Line Security, Cuts Costs

A Simple Idea, Proven by Rigorous Science


A multicenter randomized controlled trial published in Critical Care Medicine is drawing global attention for its practical impact.

The STICKY Trial, led by Australian researcher Nicole Marsh, RN, PhD, found that adding gum mastic liquid adhesive (Mastisol®) to standard jugular central-line dressings:

  • Cut premature dressing failure nearly in half
  • Extended wear time more than two-fold
  • Saved hospitals money
  • And showed promising signals for infection prevention

“Maintaining effective dressing securement of central venous catheters in intensive care is a
clinical priority,” says Dr. Marsh. “Our study demonstrated that Mastisol kept dressings intact longer and reduced unnecessary changes. That means the insertion wound stays continually protected from contamination, and the risk of catheter dislodgement is reduced as well.”

Across four Australian ICUs, 160 critically ill patients with jugular central venous catheters
(CVCs) were enrolled.

Premature dressing failure fell from 50 percent in the control group to 28 percent with Mastisol. Median dressing life increased from 23.8 hours to 58.5 hours, producing an average savings of AUD $11 per patient in material and labor costs.

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PICC Excellence Launches Ultrasound PIV Mastery Program

Insertion of a peripheral intravenous catheter is the most commonly performed invasive medical procedure among hospitalized patients. When coupled with ultrasound technologies for vascular visualization, well trained clinicians achieve greater first-time procedural success for peripheral IV insertions.

Nancy Moureau, RN, PhD, CRNI, CPUI, VA-BC

According to vascular access expert Nancy Moureau, RN, PhD, CRNI, CPUI, VA-BC, inconsistent and fragmented training can make it difficult for clinicians to establish competency and master the skills needed to perform successful ultrasound-guided peripheral IV insertions.

To address the lack of standardized UGPIV training, Moureau and her team at PICC Excellence developed a comprehensive training program, which recently became the first educational program to be recognized with a Seal of Approval from the Infusion Nurses Society. The INS Seal of Approval is designed to reflect the credibility of education, competency-based training and content that adheres to INS standards for infusion-related practices (see sidebar below).

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The Evolution of Thought Leadership in the MedTech Industry: Insights from Jeff Jones

In the rapidly advancing world of medical technology, establishing credibility and trust is paramount. And one of the best ways to establish that credibility is to seek—and follow—the advice of prominent experts in a particular medtech field. Combined with a strategic public relations strategy, such key opinion leaders (KOLs) can then help raise awareness and provide an invaluable validation of a technology’s importance and value. Together, thought leaders and PR experts enable businesses to gain media exposure, present results at scientific meetings, and secure speaking engagements at industry conferences, thus raising the companies’ visibility and credibility.

Jeffrey Jones, Managing Partner at The Deerborne Group, a global diagnostics and life sciences consulting firm, has learned the importance of key opinion leaders over the course of a long and successful career at both Fortune 500 companies like Abbott, Bayer, and Quest Diagnostics and venture-backed startups like Agendia, which offers genomic testing for breast cancers. Here are his insights:

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In Controversy over Transducer Disinfection, Intersocietal Position Statement Earns Broad Support

Over the past decade, there has been a dramatic increase in the adoption of point-of-care (POC) ultrasound to improve patient care across a wide variety of medical specialties, including cardiology, emergency medicine, obstetrics and gynecology, orthopedics, vascular access, and more. But the rapid dissemination of POC ultrasound among new medical specialties, combined with conflicting guidance from clinical organizations, has led to widespread confusion about the infection control practices appropriate for POC ultrasound equipment.

In this blog post, we examine the rise of POC ultrasound, the controversy and confusion surrounding transducer disinfection practices, and the details behind a 2021 Intersocietal Position Statement that provides some much-needed clarity on the topic.

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Knowledge is Power – Why you should #KnowYourBiomarker

Republished with permission from the blog of AJ Patel. This is the second post in a series on advances in genomic testing and the future of cancer treatment — see the first post here.

When I was diagnosed 8 years ago with non-small cell lung cancer (NSCLC), I was told I had 6 months to live. It was the worst time of my life, and I wallowed in misery for nearly a week before I decided I needed to take action. I turned to the internet, which at first did nothing to alleviate my misery. But then I stumbled upon the patient advocacy organization LUNGevity and made a phone call that changed the trajectory of my entire diagnosis.

​That one call—and the connections and information that came out of it—are the reason I’m alive today.

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Breaking Down Barriers – Improving Access to Comprehensive Biomarker Testing for Cancer Patients

This is the first in a series on advances in genomic testing and the future of cancer treatment.

The last two decades have brought remarkable advances in cancer treatment with the use of precision medicine. Twenty years ago, the major weapon doctors had against most advanced cancers was a harsh regimen of chemotherapy — a one-size-fits-all treatment that leaves patients debilitated while offering limited survival.

The shift to more targeted treatments began after researchers discovered that many cancers are driven by mutations in specific genes. This was most robustly exemplified in non-small cell lung cancer (NSCLC). Pharmaceutical companies have now developed more than two dozen drugs for patients with NSCLC that directly target specific genes and mutations, leading to better overall outcomes.

The impact of these advances “has been enormous,” says Dr. Wendy Levin, Chief Medical Officer at Biofidelity, a cancer diagnostic company. “If we can get a patient on a targeted agent that’s more effective and better tolerated, we know that they will have a major survival advantage.”

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Is it Time to Move Beyond CLABSI?

When it comes to infection control in vascular access, central line-associated bloodstream infections (CLABSIs) certainly get the most attention. Yet the medical community is increasingly recognizing how infections associated with other types of vascular access devices are putting patients at risk.

Take peripheral IV (PIV) catheters, the most commonly used type of vascular access device. Nearly 90 percent of hospitalized patients require a PIV at some point during their stay, and PIV usage far outnumbers that of central vascular access devices (CVAD). PIVs, therefore, account for an infection rate that approaches the CVAD infection rate in absolute terms.

Yet there is currently no mandatory reporting system for bloodstream infections associated with PIVs in the U.S., making it one of the most underreported types of infections in vascular access. Epidemiologist Robert Garcia, an infection preventionist with 40 years of hospital experience, shares these concerns — and he has a plan to address this significant patient safety issue.

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2021 INS Standards Highlight Anti-Reflux Technology for Needleless Connectors

Guest post by Nancy Moureau, RN, PhD, CEO of PICC Excellence

In vascular access, needleless connectors (NC) are now recommended worldwide to maintain closed IV systems and promote safety by preventing needlestick injuries. Over the past 25 years, many different NCs have come onto the market, with wide variations in design and function among the various types. As a result, there is a lot of confusion among clinicians regarding the proper use and management of these small yet complex devices, which can have serious patient safety implications.

Fortunately, the Infusion Nurses Society provides some clarity on this issue by significantly expanding its guidance on NCs in the 2021 Infusion Therapy Standards of Practice. This includes clearer definitions of the various types of NC technology and emphasizes the importance of understanding how to use each type properly to minimize blood reflux.

Many clinicians are not aware of the impact blood reflux can have, or view it as a minor issue that can be easily addressed with proper flushing. However, evidence is mounting that reflux is largely avoidable and leads to many complications that seriously impact patient safety.

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UGPIV Practices: Are they jeopardizing patient safety?

A new continuing education program details how a lack of standardized policies related to ultrasound-guided peripheral IV (UGPIV) catheter insertions can negatively impact patient safety. The webinar also suggests UGPIV performance improvement initiatives that “can help to create a culture of safety across the healthcare continuum,” according to presenter Nancy Moureau, RN, PhD, an internationally recognized expert and consultant in vascular access and CEO of PICC Excellence.

The on-demand webcast, Patient Safety and Ultrasound-Guided Peripheral IV Placement: The Need for Standardized Practices, offers 1 contact hour of continuing education for nurses. It is sponsored by Parker Laboratories.

“While the use of ultrasound guidance to improve success during PIV catheter placements is becoming more common, suboptimal aseptic technique and variations in supply usage poses a very serious risk to patients,” said Dr. Moureau. “To increase safety during UGPIV insertions, healthcare organizations should adopt a multidisciplinary approach to standardize policies and procedures based on current evidence and recommendations, while at the same identifying opportunities for pragmatic, incremental improvements.”

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